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gene_networks_inference [2018/12/14 15:34] – [Related work] admingene_networks_inference [2019/01/15 14:54] – [Related work] admin
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   - Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma, [[http://www.cell.com/cell/abstract/S0092-8674(17)30639-6?innerTabgraphical_S0092867417306396|Cell]], 2017 [{{:ally-copmprehensive_and_integrative_genomic_char_of_hcc-cell-2017.pdf|pdf}}  ]. \\  TCGA's HCC data and subtyping using DNA copy number, DNA methylation, mRNA expression, miRNA expression and RPPA (protein expression). Links to the MDACC dataset with 100 HCC samples.   - Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma, [[http://www.cell.com/cell/abstract/S0092-8674(17)30639-6?innerTabgraphical_S0092867417306396|Cell]], 2017 [{{:ally-copmprehensive_and_integrative_genomic_char_of_hcc-cell-2017.pdf|pdf}}  ]. \\  TCGA's HCC data and subtyping using DNA copy number, DNA methylation, mRNA expression, miRNA expression and RPPA (protein expression). Links to the MDACC dataset with 100 HCC samples.
   - Guillamot, Maria, Luisa Cimmino, and Iannis Aifantis. "The impact of DNA methylation in hematopoietic malignancies." [[http://www.cell.com/trends/cancer/pdf/S2405-8033(15)00089-8.pdf|Trends in cancer]] 2.2 (2016): 70-83. \\  Reviews and references DNA methylation studies and datasets on AML. E.g., [[http://www.sciencedirect.com/science/article/pii/S1535610809004206|Figueroa]] et al. used DNA methylation for classification of 344 AML cases. [[http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002781|Akalin]] et al. related DNA methylation patterns with mutations in 5 AML cases. "The methylation status of specific genes can predict the future survival of AML patients, suggesting that DNA methylation is a biomarker for clinical outcome" see e.g., Figueroa et al, [[http://www.bloodjournal.org/content/bloodjournal/113/6/1315.full.pdf?sso-checked=true|Jiang]] 2009 (studied MDS to AML progression in 184 cases), and [[http://www.bloodjournal.org/content/115/3/636.long?sso-checked=true|Bullinger]] 2010 (analyzed 92 genomic regions in 182 patients).   - Guillamot, Maria, Luisa Cimmino, and Iannis Aifantis. "The impact of DNA methylation in hematopoietic malignancies." [[http://www.cell.com/trends/cancer/pdf/S2405-8033(15)00089-8.pdf|Trends in cancer]] 2.2 (2016): 70-83. \\  Reviews and references DNA methylation studies and datasets on AML. E.g., [[http://www.sciencedirect.com/science/article/pii/S1535610809004206|Figueroa]] et al. used DNA methylation for classification of 344 AML cases. [[http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002781|Akalin]] et al. related DNA methylation patterns with mutations in 5 AML cases. "The methylation status of specific genes can predict the future survival of AML patients, suggesting that DNA methylation is a biomarker for clinical outcome" see e.g., Figueroa et al, [[http://www.bloodjournal.org/content/bloodjournal/113/6/1315.full.pdf?sso-checked=true|Jiang]] 2009 (studied MDS to AML progression in 184 cases), and [[http://www.bloodjournal.org/content/115/3/636.long?sso-checked=true|Bullinger]] 2010 (analyzed 92 genomic regions in 182 patients).
 +  - John [[https://www.youtube.com/watch?v=Vyhq7GZFnes|Quackenbush's]] talk entitled: "Using Networks to Understand the Genotype-Phenotype Connection" \\
  
  \\ **Related software**  \\ **Related software**