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multiomics_analysis_for_dementia [2019/02/14 16:18] – [Data] adminmultiomics_analysis_for_dementia [2019/06/07 14:55] – [Related work] admin
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   - Exome Sequencing Project ([[http://evs.gs.washington.edu|ESP]]), richly-phenotyped for heart, lung and blood disorders.   - Exome Sequencing Project ([[http://evs.gs.washington.edu|ESP]]), richly-phenotyped for heart, lung and blood disorders.
   - Alzheimer's Disease Sequencing Project ([[https://www.niagads.org/adsp/content/study-design|ADSP]]), WES and WGS of thousands of AD and control samples.   - Alzheimer's Disease Sequencing Project ([[https://www.niagads.org/adsp/content/study-design|ADSP]]), WES and WGS of thousands of AD and control samples.
-  - Allen Brain [[http://portal.brain-map.org/|Atlases]] has many different data types, but from a few mouse and human samples. RNA-Seq data of hundreds of dementia cases.+  - Allen Brain [[http://portal.brain-map.org/|Atlases]] has many different [[http://aging.brain-map.org/overview/home|downloadable]] data types, but from a few mouse and human samples. RNA-Seq data of hundreds of dementia cases.
   - The Alzheimer's Disease Neuroimaging Initiative ([[http://adni.loni.usc.edu/data-samples/data-types/|ADNI]]) has genetic and imaging data of 1-3 K samples.   - The Alzheimer's Disease Neuroimaging Initiative ([[http://adni.loni.usc.edu/data-samples/data-types/|ADNI]]) has genetic and imaging data of 1-3 K samples.
   - The Image and Data Archive ([[https://ida.loni.usc.edu|IDA]]) contains mostly image data on 43,290 subjects from 119 studies.   - The Image and Data Archive ([[https://ida.loni.usc.edu|IDA]]) contains mostly image data on 43,290 subjects from 119 studies.
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 ===== Related work ===== ===== Related work =====
  
-1- An interactive timeline of Alzheimer's disease by [[https://www.alzforum.org/timeline/alzheimers-disease#2010|AlzForum]].+  - An interactive timeline of Alzheimer's disease by [[https://www.alzforum.org/timeline/alzheimers-disease#2010|AlzForum]]. 
 +  - Mathys, Hansruedi, et al. "Single-cell transcriptomic analysis of Alzheimer’s disease." Nature ([[https://www.nature.com/articles/s41586-019-1195-2|2019]]). \\  Radek's summary: "Showing single cell transcriptomic analysis on brain tissues from ~50 patients with Alzheimer's disease. Subpopulations of glia and neurons expressed different gene signatures associated with AD. These enormous cataloging data may help to further pinpoint pathways associated with AD.", and his {{:wiki:img_20190516_162440263.jpg?linkonly|plan}}.