Determine biomarkers for Alzheimer's and other neurodegenerative diseases using comprehensive analysis of various data including genomics, epigenomics, metabolomics, proteomics, etc.

Large cohorts with phenotype data on dementia are available through:

1. The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
2. The Trans-Omics for Precision Medicine (TOPMed) program. The TOPMed Omics Survey includes Framingham Heart Study (FHS) details.

Dr. Sudha Seshadri, the Founding Director of The Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases.

Network analysis on proteome data of Fremingham cohort