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multiomics_analysis_for_dementia [2018/11/01 15:43] – [Data] adminmultiomics_analysis_for_dementia [2018/11/01 18:39] – [Data] admin
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   - Alzheimer's Disease Sequencing Project ([[https://www.niagads.org/adsp/content/study-design|ADSP]]), WES and WGS of thousands of AD and control samples.   - Alzheimer's Disease Sequencing Project ([[https://www.niagads.org/adsp/content/study-design|ADSP]]), WES and WGS of thousands of AD and control samples.
   - Allen Brain [[http://portal.brain-map.org/|Atlases]] has many different data types, but from a few mouse and human samples. RNA-Seq data of hundreds of dementia cases.   - Allen Brain [[http://portal.brain-map.org/|Atlases]] has many different data types, but from a few mouse and human samples. RNA-Seq data of hundreds of dementia cases.
 +  - The Alzheimer's Disease Neuroimaging Initiative ([[http://adni.loni.usc.edu/data-samples/data-types/|ADNI]]) has genetic and imaging data of 1-3 K samples.
 +  - The Image and Data Archive ([[https://ida.loni.usc.edu|IDA]]) contains mostly image data on 43,290 subjects from 119 studies.
 +  - Several studies share their data through Accelerating Medicines Partnership - Alzheimer's Disease ([[https://www.synapse.org/#!Synapse:syn5550382|AMP-AD]]) including:
 +      - The Adult Changes in Thought ([[https://www.synapse.org/#!Synapse:syn5759376|ACT]]) measured ~4K __proteins__  in ~50 brains and performed WGCNA. Also, proteome data in BLSA (~100 brains), Banner (~200).
 +      - CHDWB and HBTRC, each has a __gene expression__  profile from ~500 brains, MC-CAA (75), MCADGS (~100 RNA-Seq and GWAS samples), .
 +  -
  
  
 ===== Collaborators ===== ===== Collaborators =====
-Dr. [[http://gsbs.uthscsa.edu/faculty/sudha-seshadri-m.d.-dm|Sudha Seshadri]], the Founding Director of The Glenn [[https://biggsinstitute.org/|Biggs Institute]] for Alzheimer's & Neurodegenerative Diseases.+ 
 +Dr. [[http://gsbs.uthscsa.edu/faculty/sudha-seshadri-m.d.-dm|Sudha Seshadri]], the Founding Director of The Glenn [[https://biggsinstitute.org/|Biggs Institute]] for Alzheimer's & Neurodegenerative Diseases, and [[https://biggsinstitute.org/team-member/claudia-l-satizabal-phd/|Dr. Claudia Satizabal]].
  
 ===== Subprojects ===== ===== Subprojects =====
-Network analysis on [[https://docs.google.com/document/d/1K89u6OubQUXAycg6JaEqzNgv18ybRy4QWcG_3UVQBuQ/edit|proteome]] data of Fremingham cohort  + 
 +Network analysis on [[https://docs.google.com/document/d/1K89u6OubQUXAycg6JaEqzNgv18ybRy4QWcG_3UVQBuQ/edit|proteome]] data of Fremingham cohort 
 + 
 + 
 +=====   ===== 
 +