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multiomics_analysis_for_dementia [2018/11/01 16:48] – [Subprojects] admin | multiomics_analysis_for_dementia [2018/11/01 18:55] – [Data] admin |
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- The Alzheimer's Disease Neuroimaging Initiative ([[http://adni.loni.usc.edu/data-samples/data-types/|ADNI]]) has genetic and imaging data of 1-3 K samples. | - The Alzheimer's Disease Neuroimaging Initiative ([[http://adni.loni.usc.edu/data-samples/data-types/|ADNI]]) has genetic and imaging data of 1-3 K samples. |
- The Image and Data Archive ([[https://ida.loni.usc.edu|IDA]]) contains mostly image data on 43,290 subjects from 119 studies. | - The Image and Data Archive ([[https://ida.loni.usc.edu|IDA]]) contains mostly image data on 43,290 subjects from 119 studies. |
| - Several studies share their data through Accelerating Medicines Partnership - Alzheimer's Disease ([[https://www.synapse.org/#!Synapse:syn5550382|AMP-AD]]) including: |
| - The Adult Changes in Thought ([[https://www.synapse.org/#!Synapse:syn5759376|ACT]]) measured ~4K __proteins__ in ~50 brains and performed WGCNA. Also, proteome data in BLSA (~100 brains), Banner (~200), and UPPpilot (~200). |
| - CHDWB and HBTRC, each has a __gene expression__ profile from ~500 brains, MC-CAA (75), MCADGS (~100 RNA-Seq and GWAS samples). |
| - The Mount Sinai Brain Bank ([[https://www.synapse.org/#!Synapse:syn3159438|MSBB]]) includes proteome and gene expression profiles from hundreds of samples. |
| - The [[https://www.synapse.org/#!Synapse:syn5550404|MayoRNAseq]] includes WGS and RNA-Seq data from 275 Cerebellum (CBE) and 276 Temporal cortex (TCX) samples. |
| - The Religious Orders Study and Memory and Aging Project ([[https://www.synapse.org/#!Synapse:syn3219045|ROSMAP]]) is the richest dataset in terms of variety of data types, which includes gene expression, genom, proteome, metabolome, and image data. |
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