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r_test [2019/08/07 11:43]
217.218.215.57 [Question 1]
r_test [2020/01/23 17:09] (current)
admin [Question 2:]
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-**B)** Let's define the //impact// of a set of genes to be the p-value of a log-rank test with the null hypothesis that when all of these genes are mutated together, the survival does not change. Write a function ''​most.impact()''​ that takes as input two ''​k1''​ and ''​n1''​ integers, and in the list of ''​n1''​ most mutated genes, finds the names of the ''​k1''​ genes with the best impact. Your function should return the names of the best ''​k1''​ genes, and also their impact. Run your function for ''​k1=3'',​ and ''​n1=3'',​ ''​10'',​ and ''​100''​. What is the biological interpretation of your results?+**B)** Let's define the //impact// of a set of genes to be the p-value of a log-rank test with the null hypothesis that when all of these genes are mutated together, the survival does not change. Write a function ''​most.impact()''​ that takes as input two ''​k1''​ and ''​n1''​ integers, and in the list of ''​n1''​ most mutated genes, finds the names of the ''​k1''​ genes with the best impact. Your function should return the names of the best ''​k1''​ genes (i.e., the set of genes with the best log-rank p-value), and also their impact. Run your function for ''​k1=3'',​ and ''​n1=3'',​ ''​10'',​ and ''​100''​. What is the biological interpretation of your results?
  
 __Hint:__ Use the ''​utils::​c?​m?​n()''​ function, where you need to guess the question marks. __Hint:__ Use the ''​utils::​c?​m?​n()''​ function, where you need to guess the question marks.