# Differences

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r_test [2019/08/07 11:43] 217.218.215.57 [Question 1] |
r_test [2020/01/23 17:09] (current) admin [Question 2:] |
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- | **B)** Let's define the //impact// of a set of genes to be the p-value of a log-rank test with the null hypothesis that when all of these genes are mutated together, the survival does not change. Write a function ''most.impact()'' that takes as input two ''k1'' and ''n1'' integers, and in the list of ''n1'' most mutated genes, finds the names of the ''k1'' genes with the best impact. Your function should return the names of the best ''k1'' genes, and also their impact. Run your function for ''k1=3'', and ''n1=3'', ''10'', and ''100''. What is the biological interpretation of your results? | + | **B)** Let's define the //impact// of a set of genes to be the p-value of a log-rank test with the null hypothesis that when all of these genes are mutated together, the survival does not change. Write a function ''most.impact()'' that takes as input two ''k1'' and ''n1'' integers, and in the list of ''n1'' most mutated genes, finds the names of the ''k1'' genes with the best impact. Your function should return the names of the best ''k1'' genes (i.e., the set of genes with the best log-rank p-value), and also their impact. Run your function for ''k1=3'', and ''n1=3'', ''10'', and ''100''. What is the biological interpretation of your results? |

__Hint:__ Use the ''utils::c?m?n()'' function, where you need to guess the question marks. | __Hint:__ Use the ''utils::c?m?n()'' function, where you need to guess the question marks. |