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Rapamycin effects on aging-associated pathologies

Objectives

Rapamycin is an inhibitor of the mTOR pathway, which has been used in preventing rejection of solid organ allografts. In this multi-PI study on an older age healthy human cohort, we assess the usability and efficacy of Rapamycin in improving physical performance, cardiac and vascular health, and immune outcomes. This approach is motivated by the promising results that were observed in prior studies on mice models. Oncinfo contributes in this study through analysis of gene expression and DNA methylation profiles.

Data

  1. DNa methylation data of

Collaborators