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rapamycin [2019/07/29 17:31] – [Data] 89.187.177.110rapamycin [2019/07/29 18:46] (current) – [DNA methylation analysis] admin
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 ====== Rapamycin effects on aging-associated pathologies ====== ====== Rapamycin effects on aging-associated pathologies ======
  
-====== Rapamycin effects on aging-associated pathologies ====== 
  
 ===== Objectives ===== ===== Objectives =====
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   - DNA methylation data of {{:wiki:public:plan_discussed_with_habil_07_24_19.docx|29 subjects}}  were measured in 2019 using Infinium [[https://support.illumina.com/downloads/infinium-methylationepic-v1-0-product-files.html|MethylationEpic]] V1 Array. PBMC samples were collected before and after Rapamycin (16 subjects) and placebo (13 subjects) treatment for 6-8 weeks.   - DNA methylation data of {{:wiki:public:plan_discussed_with_habil_07_24_19.docx|29 subjects}}  were measured in 2019 using Infinium [[https://support.illumina.com/downloads/infinium-methylationepic-v1-0-product-files.html|MethylationEpic]] V1 Array. PBMC samples were collected before and after Rapamycin (16 subjects) and placebo (13 subjects) treatment for 6-8 weeks.
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 ===== Collaborators ===== ===== Collaborators =====
  
-Dr. [[https://wp.uthscsa.edu/mimg/team-member/ellen-kraig-ph-d/|Ellen Kraig]], an immunologist from the University of Texas Health Science Center at San Antonio. +Dr. [[https://wp.uthscsa.edu/mimg/team-member/ellen-kraig-ph-d/|Ellen Kraig]], an immunologist, and Dr. [[https://www.uthscsa.edu/academics/biomedical-sciences/faculty/profile/0V71EU5IM/Kellogg,-Dean-L.-Jr.|Dean Kellogg]], a physiologist, both from the University of Texas Health Science Center at San Antonio.
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-Dr. [[https://www.uthscsa.edu/academics/biomedical-sciences/faculty/profile/0V71EU5IM/Kellogg,-Dean-L.-Jr.|Dean Kellogg]], a physiologist from the University of Texas Health Science Center at San Antonio. +
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-===== Collaborators =====+
  
-Dr. [[https://wp.uthscsa.edu/mimg/team-member/ellen-kraig-ph-d/|Ellen Kraig]], an immunologist from the University of Texas Health Science Center at San Antonio. 
  
-Dr. [[https://www.uthscsa.edu/academics/biomedical-sciences/faculty/profile/0V71EU5IM/Kellogg,-Dean-L.-Jr.|Dean Kellogg]], a physiologist from the University of Texas Health Science Center at San Antonio.+===== DNA methylation analysis =====
  
 +We follow the Bioconductor [[https://www.bioconductor.org/packages/release/workflows/vignettes/methylationArrayAnalysis/inst/doc/methylationArrayAnalysis.html#differential-methylation-analysis|workflow]] to identify the probes and regions that are differentially methylation due to Rapamycin treatment.