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serum_biomarkers_for_neurodegeneration [2019/12/03 23:11] – admin | serum_biomarkers_for_neurodegeneration [2019/12/25 01:51] (current) – [Analysis] admin | ||
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+ | ====== Serum biomarkers for neurodegeneration ====== | ||
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===== Objectives ===== | ===== Objectives ===== | ||
- | Identify novel serum biomarkers for neurodegeneration that allow accurate diagnosis of Alzheimer' | + | Identify novel serum biomarkers for neurodegeneration that allow accurate diagnosis of Alzheimer' |
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+ | ===== Data ===== | ||
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+ | - Six proteins were measured in blood samples of ~1200 Hispanic and ~500 non-Hispanic white participants. Covariates include gender, education, and age. | ||
+ | - The cognitive status of participants were assessed in several visits over years. The number of visits and time intervals between visits vary across participants. | ||
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+ | ===== Collaborators ===== | ||
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+ | Dr. Sudha [[https:// | ||
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+ | ===== Analysis ===== | ||
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+ | - Linear models. | ||
+ | - Regularized regression, e.g., the LASSO and [[https:// | ||
+ | - Hidden Markov Models (HMM). | ||
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+ | ===== Related work ===== | ||
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+ | - Eagan, Danielle E., et al. " | ||